2017

Kilfoyle, A.K., Jermain, R.F., Dhanak, M.R., Huston, J.P., & Spieler, R.E. (2017). Effects of EMF emissions from undersea electric cables on coral reef fishes. Bioelectromagnetics, in press.

Chao, O. Y., Nikolaus, S., Brandão, M. L., Huston, J. P., de Souza Silva, M. A. (2017). Interaction between the medial prefrontal cortex and hippocampal CA1 area is essential for episodic-like memory in rats. Neurobiology of Learning and Memory, 141, 72-77. [undefinedabstract] [undefinedFull Text]

Dere, E., Dere, D., de Souza Silva, M. A., Huston, J. P., & Zlomuzica, A. (2017). Fellow travellers: working memory and mental time travel in rodents. Behavioural Brain Research. [undefinedabstract] [undefinedFull Text]

Nikolaus, S., Beu, M., de Souza Silva, M. A., Huston, J. P., Antke, C., Müller, H. W., & Hautzel, H. (2017). GABAergic control of neostriatal dopamine D 2 receptor binding and behaviors in the rat. Pharmacology Biochemistry and Behavior, 153, 76-87. [undefinedabstract] [undefinedFull Text]

Talbot, T., Mattern, C., de Souza Silva, M. A., & Brandão, M. L. (2017). Intranasal administration of dopamine attenuates unconditioned fear in that it reduces restraint-induced ultrasound vocalizations and escape from bright light. Journal of Psychopharmacology, 0269881116686882. [undefinedabstract] [undefinedFull Text]

2016

Huston, J.P., Komorowski, M., de Souza Silva, M.A., Lamounier-Zepter, V., Nikolaus, S., Mattern, C., Müller, C.P., & Topic, B. (2016). Chronic corticosterone treatment enhances extinction-induced depression in aged rats. Hormones and behavior, 86, 21-26. [undefinedabstract] [undefinedFull Text]

Chao, O. Y., Huston, J. P., Nikolaus, S., & de Souza Silva, M. A. (2016). Concurrent assessment of memory for object and place: Evidence for different preferential importance of perirhinal cortex and hippocampus and for promnestic effect of a neurokinin-3 R agonist. Neurobiology of learning and memory, 130, 149-158. [undefinedabstract] [undefinedFull Text]

Abdel-Hafiz, L., Chao, O. Y., Huston, J. P., Nikolaus, S., Spieler, R. E., de Souza Silva, M. A., & Mattern, C. (2016). Promnestic effects of intranasally applied pregnenolone in rats. Neurobiology of learning and memory, 133, 185-195. [undefinedabstract] [undefinedFull Text]

Nikolaus, S., Beu, M., Angelica De Souza Silva, M., Huston, J. P., Hautzel, H., Antke, C., & Müller, H. W. (2016). DAT versus D2 receptor binding in the rat striatum: l‐DOPA‐induced motor activity is better predicted by reuptake than release of dopamine. Synapse, 70(9), 369-377. [undefinedabstract]

Schulz, D., Henn, F. A., Petri, D., & Huston, J. P. (2016). Rats bred for helplessness exhibit positive reinforcement learning deficits which are not alleviated by an antidepressant dose of the MAO-B inhibitor deprenyl. Neuroscience, 329, 83-92. [undefinedabstract] [undefinedFull Text]

de Souza Silva M. A., Mattern C., Decheva C., Huston J. P., Sadile A. G., Beu M., Müller H.-W., & Nikolaus S. (2016). Intranasal Dopamine Reduces In Vivo [(123) I] FP-CIT Binding to Striatal Dopamine Transporter: Correlation with Behavioral Changes and Evidence for Pavlovian Conditioned Dopamine Response. Frontiers in behavioral neuroscience, 10, 80-80. [undefinedabstract] [undefinedFull Text]

Trossbach S. V., Bader V., Hecher L., Pum M. E., Masoud S. T., Prikulis I., Schäble S., de Souza Silva M. A., Su P., Boulat B., Chwiesko C., Poschmann G., Stuhler K., Lohr K. M., Stout K. A., Oskamp A., Godsave S. F., Muller-Schiffmann A., Bilzer T., Steiner H., Peters P. J., Bauer A., Sauvage M., Ramsey A. J., Miller G. W., Liu F., Seeman P., Brandon N. J., Huston J. P., & Korth C. (2016) Misassembly of full-length Disrupted-in-Schizophrenia 1 protein is linked to altered dopamine homeostasis and behavioral deficits. Molecular psychiatry, advance online publication. [undefinedabstract] [undefinedFull Text]

Vomund, S., de Souza Silva, M. A., Huston, J. P., & Korth, C. (2016). Behavioral Resilience and Sensitivity to Locally Restricted Cortical Migration Deficits Induced by In Utero Knockdown of Disabled-1 in the Adult Rat. Cerebral Cortex, bhw060. [undefinedabstract] [undefinedFull Text]

Huston J. P., Kornhuber J., Mühle C., Japtok L., Komorowski M., Mattern C., Reichel M., Gulbins E., Kleuser B., Topic B., de Souza Silva M. A. and Müller C. P. (2016) A sphingolipid mechanism for behavioral extinction. Journal of neurochemistry, 137(4), 589-603. [undefinedabstract] [undefinedFull Text]

Müller-Schiffmann A., Herring A., Abdel-Hafiz L., Chepkova A. N., Schäble S., Wedel D., Horn A. H., Sticht H., de Souza Silva M. A., Gottmann K., Sergeeva O. A., Huston J. P., Keyvani K. and Korth C. (2016) Amyloid-beta dimers in the absence of plaque pathology impair learning and synaptic plasticity. Brain, 139(2), 509-525. [undefinedabstract] [undefinedFull Text]

Nikolaus S., Beu M., de Souza Silva M. A., Huston J. P., Hautzel H., Mattern C., Antke C., & Müller H. W. (2016) Corrigendum: Relationship Between L-DOPA-Induced Reduction in Motor and Exploratory Activity and Striatal Dopamine D2 Receptor Binding in the Rat. Frontiers in behavioral neuroscience, 10, 36-36. [undefinedabstract] [undefinedFull Text]

Chao, O. Y., Huston, J. P., Li, J. S., Wang, A. L., & de Souza Silva, M. A. (2016). The medial prefrontal cortex—lateral entorhinal cortex circuit is essential for episodic‐like memory and associative object‐recognition. Hippocampus, 26(5), 633-645. [undefinedabstract] [undefinedFull Text]

de Souza Silva, M. A., Huston, J. P., Wang, A. L., Petri, D., & Chao, O. Y. H. (2016). Evidence for a specific integrative mechanism for episodic memory mediated by AMPA/kainate receptors in a circuit involving medial prefrontal cortex and hippocampal CA3 region. Cerebral Cortex, 26(7), 3000-3009. [undefinedabstract] [undefinedFull Text]

2015

Petri, D., de Souza Silva, M. A., Chao, O. H., Schnitzler, A., & Huston, J. P. (2015). Serotonergic interaction between medial prefrontal cortex and mesotelencephalic DA system underlies cognitive and affective deficits in hemiparkinsonian rats. Neuroscience, 307, 51-63. [undefinedabstract] [undefinedFull Text]

Huston, A. J., & Huston, J. P. (2015). Aesthetic evaluation of art: A formal approach. Art, Aesthetics, and the Brain, 479-499. [undefinedFull Text]

Huston, J. P., Nadal, M., Mora, F., Agnati, L. F., & Conde, C. J. C. (Eds.). (2015). Art, Aesthetics, and the Brain. OUP Oxford. [undefinedOUP link]

Biesdorf, C., Wang, A. L., Topic, B., Petri, D., Milani, H., Huston, J. P., & de Souza Silva, M. A. (2015). Dopamine in the nucleus accumbens core, but not shell, increases during signaled food reward and decreases during delayed extinction. Neurobiology of learning and memory, 123, 125-139. [undefinedabstract] [undefinedFull Text]

Chao, O. Y., Wang, A. L., Nikolaus, S., & de Souza Silva, M. A. (2015). NK 3 receptor agonism reinstates temporal order memory in the hemiparkinsonian rat. Behavioural brain research, 285, 208-212. [undefinedabstract] [undefinedFull Text]

Zlomuzica, A., Dere, D., Binder, S., Silva, M. A. D. S., Huston, J. P., & Dere, E. (2016). Neuronal histamine and cognitive symptoms in Alzheimer's disease. Neuropharmacology, 106, 135-145. [undefinedabstract] [undefinedFull Text]

Amato, D., Pum, M. E., Groos, D., Lauber, A. C., Huston, J. P., Carey, R. J., de Souza Silva, M. A., & Müller, C. P. (2015). Neuropharmacology of light-induced locomotor activation. Neuropharmacology, 95, 243-251. [undefinedabstract] [undefinedFull Text]

Goodson, N. B., Brockhoff, B. L., Huston, J. P., & Spieler, R. E. (2015). Time-dependent bidirectional effects of chronic caffeine on functional recovery of the dorsal light reflex after hemilabyrinthectomy in the goldfish Carassius auratus. Neuroscience, 292, 112-117. [undefinedabstract] [undefinedFull Text]

2014

Ruocco, L.A., Treno, C., Gironi Carnevale, U.A., Arra, C., Boatto, G., Pagano, C., Tino, T., Nieddu, M., Michel, M., Prikulis, I., Carboni, E., De Souza Silva, M.A., Huston, J.P., Sadile, A.G., Korth, C. (2014) Immunization with DISC1 protein in an animal model of ADHD influences behavior and excitatory amino acids in prefrontal cortex and striatum. Amino Acids [undefinedabstract] [undefinedFull Text]

Nikolaus, S., Beu, M., De Souza Sliva, M.A., Huston, J.P., Hautzel, H., Chao, O.Y., Antke, C., Müller, H.-W. (2014) Relationship between L-DOPA-induced reduction in motor and exploratory activity and degree of DAT binding in the rat. Front Behav Neurosci [undefinedabstract] [undefinedFull Text]

Trossbach, S.V., Fehsel, K., Henning, U., Winterer, G., Luckhaus, C., Schäble, S., de Souza Silva, M.A. (2014) Peripheral DISC1 protein levels as a trait marker for schizophrenia and modulating effects of nicotine. Behav Brain Res. [undefinedabstract] [undefinedFull Text]

Chao, O.Y., Nikolaus, S., Huston, J.P., de Souza Silva, M.A., (2014) The Neurokinin-3 receptor agonist senktide fascilitates the integration of memories for object, place and temporal order into episodic memory. Neurobiol Lern Mem. [undefinedabstract] [undefinedFull text]

Chao, O.Y., Wang, A.-L., Nikolaus, S., de Souza Silva, M.A. (2014) NK3 receptor agonism reinstates temporal order memory in the hemiparkinsonian rat. Behav Brain Res. [undefinedabstract] [undefinedFull text]

Ruocco, L.A., Treno, C., Gironi Carnevale, U.A., Arra, C., Mattern, C., Huston, J.P., de Souza Silva, M.A., Nikolaus, S., Scorziello, A. , Nieddu, M., Boatto G., Illiano P., Pagano, C., Tino, A., Sadile, A.G. (2014) Prepuberal intranasal dopamine treatment in an animal model of ADHD ameliorates deficient spatial attention, working memory, amino acid transmitters and synaptic markers in prefrontal cortex, ventral and dorsal striatum. Amino Acids [undefinedabstract] [undefinedFull Text]

2013

Paes, F., Baczynski, T., Novaes, F., Marinho, T., Arias-Carrion, O., Budde, H., Sack, A.T., Huston, J.P., Almada, L.F., Carta, M., Silva, A.C., Nardi, A.E., Machado, S. (2013) Repetitive transcranial magnetic stimulation (rTMS) to treat social anxiety disorder: Case reports and a review of the literature. Clin Pract Epidemiol Ment Health [undefinedabstract] [undefinedFull text]

Dere, E., Zlomuzica, A., de Souza Silva, M.A., Huston, J.P. (2013) Object recognition in the mouse. In: Behavioral Genetics in the mouse: Volume 1. Genetics of Behavioral Phenotypes, eds. Wim E. Crusio, Frans Sluyter, Robert T. Gerlai, and Sussana Pietropaolo. Published by Cambridge university Press. Copyright Cambridge University Press 2013.

Ottis, P., Topic, B., Loos, M., Li, K.W., de Souza Silva, M.A., Schulz, D., Smit, A.B., Huston, J.P., Korth, C. (2013) Aging-induced changes in the rat hippocampus identify ARP3, NEB2 and BRAG2 as molecular circuitry for cognitive impairment. PLoS ONE [undefinedabstract] [undefinedFull text]

de Souza Silva, M.A., Lenz, B., Rotter, A., Biermann, T., Peters, O., Ramirez, A., Jessen, F., Maier, W., Hüll, M., Schröder, J., Frölich, L., Teipel, S., Gruber, O., Kornhuber, J., Huston, J.P., Müller, C.P., Schäble, S. (2013) Neurokinin3 receptor as a target to predict and improve learning and memory in the aged organism. Proc Natl Acad Sci [undefinedabstract] [undefinedFull text]

Nikolaus, S., Beu, M., Hautzel, H., de Souza Silva, A.M., Antke, C., Wirrwar, A., Huston, J.P., Müller, H.W. (2013) Effects of L-DOPA on striatal iodine-123-FP-CIT binding and beahvioral parameters in the rat. Nuc Med Comm [undefinedabstract] [undefinedFull text]

Nikolaus, S., de Souza Silva, M.A., Hautzel, H., Müller, H.W. (2013) The neurotachykinin NK1 receptor - A novel target for diagnotics and therapy. Cur Mol Img [undefinedabstract]

Morin, C., de Souza Silva, M.A., Müller, C.P., Hardigan, P., Spieler, R.E. (2013). Active avoidance learning in zebrafish (Danio rerio)- The role of sensory modality and inter-stimulus interval. Behav Brain Res [undefinedabstract] [undefinedFull Text]

Petri, D., Pum, M., Vesper, J., Huston, J.P., Schnitzler, A. (2013) GABAA-receptor activation in the subthalamic nucleus compensates behavioral asymmetries in the hemiparkinsonian rat. Behav Brain Res [undefinedabstract] [undefinedFull Text]

Barros, M., Dempster, E.L., Illott, N., Chabrawi, S., Maior, R.S., Tomaz, C., De Souza Silva, M.A., Huston, J.P., Mill, J., Müller, C.P. (2013). Decreased methylation of the NK3 receptor coding gene (TACR3) after cocaine-induced place preference in marmoset monkeys. Addict. Biol. [undefinedabstract] [undefinedFull Text]

Huston, J.P., Silva, M.A., Komorowski, M., Schulz, D., Topic, B. (2013). Animal models of extinction-induced depression: loss of reward and its consequences. Neurosci Biobehav Rev [undefinedabstract] [undefinedFull text]

Chao, O.Y., Pum, M.E., Huston, J.P., (2013). The interaction between the dopaminergic forebrain projections and the medial prefrontal cortex is critical for memory of objects: Implications for Parkinson's disease. Exp. Neurol.
[undefinedabstract] [undefinedFull text]

Huston, J.P., Silva, M.A., Topic, B., Muller, C.P., (2013). What's conditioned in conditioned place preference? Trends Pharmacol. Sci. [undefinedabstract] [undefinedFull text]

Melamed, J.L., de Souza Silva, M.A., Tomaz, C., Muller, C.P., Huston, J.P., Barros, M., (2013). Sensitization of hypervigilance effects of cocaine can be induced by NK3 receptor activation in marmoset monkeys. Drug Alcohol Depend. 128, 155-160. [undefinedabstract] [undefinedFull text]

2012

Broiz, A.C., Bassi, G.S., de Souza Silva, M.A., Brandao, M.L. (2012) Effects of neurokinin-1 and 3-receptor antagonists on the defensive behavior induced by electrical stimulation of the dorsal periaqueductal gray. Neurosci, 201, 134-145. [undefinedabstract] [undefinedFull Text]

Fernandes AR, Easton AC, De Souza Silva MA, Schumann G, Müller CP, Desrivières S. (2012) Lentiviral-mediated gene delivery reveals distinct roles of nucleus accumbens dopamine D2 and D3 receptors in novelty- and light-induced locomotor activity. Eur J Neurosci, 35, 1344-1353. [undefinedabstract] [undefinedfull Text]

Topic,B., Kroger,I., Vildirasova,P.G. & Huston,J.P. (2012) Indices of extinction-induced "depression" after operant learning using a runway vs. a cued free-reward delivery schedule. Neurobiol.Learn.Mem., 98, 329-340. [undefinedabstract] [undefinedfull text]

Bader,V., Ottis,P., Pum,M., Huston,J.P. & Korth,C. (2012) Generation, purification, and characterization of cell-invasive DISC1 protein species. J.Vis.Exp., e4132. [undefinedabstract] [undefinedfull text]

Cagni,P., Komorowski,M., Melo,G.C., Lima,T., Tomaz,C., de Souza Silva,M.A., Huston,J.P. & Barros,M. (2012) Repeated cocaine administration in marmoset monkeys induces hypervigilance-related behaviors, but no changes in locomotion and cortisol levels. Pharmacol.Biochem.Behav., 103, 279-283. [undefinedabstract] [undefinedfull text]

Komorowski,M., Huston,J.P., Klingenhegel,I., Paulat,J., Sackers,J. & Topic,B. (2012) Distance from source of reward as a marker for extinction-induced "despair": modulation by the antidepressants clomipramine and citalopram. Neuroscience, 223, 152-162. [undefinedabstract] [undefinedfull text]

Ottis,P., Koppe,K., Onisko,B., Dynin,I., Arzberger,T., Kretzschmar,H., Requena,J.R., Silva,C.J., Huston,J.P. & Korth,C. (2012) Human and rat brain lipofuscin proteome. Proteomics., 12, 2445-2454. [undefinedabstract] [undefinedfull text]

Huston,J.P., van den Brink,J., Komorowski,M., Huq,Y. & Topic,B. (2012) Antidepressants reduce extinction-induced withdrawal and biting behaviors: a model for depressive-like behavior. Neuroscience, 210, 249-257. [undefinedabstract] [undefinedfull text]

Schable,S., Huston,J.P., Barros,M., Tomaz,C. & de Souza Silva,M.A. (2012) The NK3 receptor agonist senktide ameliorates scopolamine-induced deficits in memory for object, place and temporal order. Neurobiol.Learn.Mem., 97, 235-240. [undefinedabstract] [undefinedfull text]

Chao,O.Y., Pum,M.E., Li,J.S. & Huston,J.P. (2012) The grid-walking test: assessment of sensorimotor deficits after moderate or severe dopamine depletion by 6-hydroxydopamine lesions in the dorsal striatum and medial forebrain bundle. Neuroscience, 202, 318-325. [undefinedabstract] [undefinedfull text]

Chao,O.Y., Mattern,C., Silva,A.M., Wessler,J., Ruocco,L.A., Nikolaus,S., Huston,J.P. & Pum,M.E. (2012) Intranasally applied L-DOPA alleviates parkinsonian symptoms in rats with unilateral nigro-striatal 6-OHDA lesions. Brain Res.Bull., 87, 340-345. [undefinedabstract] [undefinedfull text]

Zlomuzica,A., Viggiano,D., Degen,J., Binder,S., Ruocco,L.A., Sadile,A.G., Willecke,K., Huston,J.P. & Dere,E. (2012) Behavioral alterations and changes in Ca/calmodulin kinase II levels in the striatum of connexin36 deficient mice. Behav.Brain Res., 226, 293-300. [undefinedabstract] [undefinedfull text]

Schable,S., Huston,J.P. & Silva,M.A. (2012) Neurokinin2-R in medial septum regulate hippocampal and amygdalar ACh release induced by intraseptal application of neurokinins A and B. Hippocampus, 22, 1058-1067. [undefinedabstract] [undefinedfull text]

2011

Nikolaus, S., Larisch, R., Vosberg, H., Beu, M., Wirrwar, A., Antke, C., Kley, K., Silva, M.A., Huston, J.P., Müller, H.W. Pharmacological challenge and synaptic response - assessing dopaminergic function in the rat striatum with small animal single-photon emission tomography (SPECT) and positron emission tomography (PET). Reviews in the Neurosciences, 2011, 22(6):625-645. [abstract] [full text]

Cagni, P., Komorowski, M., Melo, G.C, Lima, T., Barros, M. Diazepam-induced decrease in anxiety-like behaviors of marmoset monkeys exposed to a novel open-field. Pharmacology, Biochemistry and Behavior, 2011, 100(3):518-528. [abstract] [full text]

Müller, C.P., Pum, M.E., Amato, D., Schüttler, J., Huston, J.P., de Souza Silva, M.A. The in-vivo neurochemistry of the brain during general anesthesia. Journal of Neurochemistry, 2011, 119(3):419-446. [abstract] [full text]

Chao, O.Y.,  Huston, J.P., von Bothmer, A., Pum, M.E. Chronic progesterone treatment of male rats with unilateral 6-OHDA lesion of the dorsal striatum exasperates parkinsonian symptoms. Neuroscience, 2011,196:228-236. [abstract] [full text]

Zlomuzica, A., Viggiano, D., Degen, J., Binder, S., Ruocco, L.A., Sadile, A.G., Willecke, K., Huston, J.P., Dere, E. Behavioral alterations and changes in CA/Calmodulin kinase II levels in the striatum of connexin36 deficient mice. Behavioural Brain Research, 2011,226(1): 293-300. [abstract] [full text]

Karrenbauer, B.D., Müller, C.P., Ho, Y.J., Spanagel, R., Huston, J.P., Schwarting, R.K.W., Pawlak, C.R. Time-dependent in-vivo effects of interleukin-2 on neurotransmitters in various cortices: Relationships with depressive-related and anxiety-like behaviour. Journal of Neuroimmunology, 2011, 237(1-2):23-32. [abstract] [full text]

Paes, F., Machado, S., Arias-Carrion, O., Velasques, B., Teixeira, S., Budde, H., Cagy, M., Piedade, P., Ribeiro, P., Huston, J.P., Sack, A.T., Nardi, A.E. The value of repetitive transcranial magnetic stimulation (rTMS) for the treatment of anxiety disorders: An integrative review. Drug Targets - CNS &  Neurological Disorders, 2011, in press. [abstract] [full text]

Schäble, S., Topic, B., Buddenberg, T.E., Petri, D., Huston, J.P., de Souza Silva, M.A. Neurokinin-3-R agonism in aged rats has anxiolytic-, antidepressant-, and promnestic-like effects and stimulates ACh release in frontal cortex, amygdala and hippocampus. European Neuropsychopharmacology, 2011, 21(6): 484-494 [abstract] [full text].

Nikolaus, S., Antke, C., Beu, M., Kley, K., Wirrwar, A., Huston, J.P., Müller, H.-W. Binding of [123l]iodobenzamide to the rat D2 receptor after challenge with various doses of methylphenidate - an in vivo imaging study with dedicated small animal SPECT. European Journal of Nuclear Medicine, 2011, 38:694-701 [abstract] [full text].

Cela-Conde, C.J., Agnati, L., Huston, J.P., Mora, F., Nadal, M. The cognitive and neural foundations of aesthetic appreciateion. Progress in Neurobiology, 2011, 94:39-48 [abstract] [full text].

Schäble, S., Huston, J.P., de Souza Silva, M. A. Neurokinin2-R in medial septum regulate hippocampal and amygdalar ACh release induced by intraseptal application of neurokinins A and B. Hippocampus, 2011, in press. [abstract] [full text]

de Oliveira, A., Reimer, A. E., de Macedo, C.E.A., de Carvalho M.C., de Souza Silva, M.A., Brandao, M.L. Conditioned fear is modulated by D2 receptor pathway connecting the ventral tegmental area and basolateral amygdala. Neurobiology of Learning and Memory, 2011, 95(1):37-45. [abstract] [full text]

2010

Zlomuzica, A., Reichinnek, S., Maxeiner, S., Both, M.m May, E., Wörsdörfer, P., Draguhn, A., Willecke, K., Dere, E. Deletion of connexin45 in mouse neurons disrupts one-trial object recognition and alters kainate-induced gamma-oscillations in the hippocampus. Physiology & Behavior, 2010, 101(2):245-253. [abstract] [full text]

Dere, E., Zlomuzica, A., de Souza Silva, M.A., Ruocco, L.A., Sadile, A.G., Huston J.P. Neuronal histamine and the interplay of memory, reinforcement and emotions. Behavioural Brain Research, 2010, 215(2):209-220.  [abstract] [full text]

Schäble, S., Huston, J.P., Dere, E., de Souza Silva, M.A. Neurokinin-2 receptor antagonism in medial septum influences temporal-order memory for objects and forebrain cholinergic activity. Peptides, 2010, 31(1): 108-115. [abstract] [full text]

2009

Pum, M.E., Schäble, S., Harooni, H.E., Topic, B., de Souza Silva, M.A., Li, J.-S., Mattern, C., Huston, J.P. Effects of intranasally applied dopamine on behavioral asymmetries in rats with unilateral 6-OHDA lesions of the nigro-striatal tract. Neuroscience, 2009, 162(1):174-183.[abstract] [full text]

Huston, J.P., Schulz, D., Topic, B. Toward an animal model of extinction-induced despair: focus on aging and physiological indices. Journal of Neural Transmission, 2009, 116(8):1029-1036. [abstract] [full text]

Pum, M.E., Huston, J.P., Müller, C.P. The role of cortical serotonin in anxiety and locomotor activity in Wistar rats. Behavioral Neuroscience, 2009, 123(2):449-454.[abstract] [full text]

Ambrée, O., Richter, H., Sachser, N., Lewejohann, L., Dere, E., de Souza Silva, M.A., Herring,A., Keyvani, K., Paulus, W., Schäbitz, W.R. Levodopa ameliorates learning and memory deficits in a murine model of Alzheimer's disease. Neurobiology of Aging, 2009, 30(8):1192-1204. [abstract] [full text]

Buddenberg, T.E., Komorowski, M., Ruocco, L.A., de Souza Silva, M.A, Topic, B.  Attenuating effects of testosterone on depressive-like behavior in the forcved swim teast in healthy male rats. Brain Research Bulletin, 2009, 79(3-4):182-186. [abstract] [full text]
Ruocco, L.A., de Souza Silva, M.A., Topic, B., Mattern, C., Huston, J.P., Sadile, A.G.  Intranasal application of dopamine reduces activity and improves attention in Naples High Excitability rats the feature the mesocortical variant of ADHD. European Neuropsychopharmacology, 2009, 19(10):693-701.[abstract] [full text]
Zlomuzica, A., Ruocco, L.A., Sadile, A.G., Huston, J.P., Dere, E.  Histamine H1 receptor knockout mice exhibit impaired spatial memory in the eight-arm radial maze. British Journal of Pharmacology, 2009, 157(1):86-91. [abstract] [full text]

de Souza Silva, M.A., Topic, B., Huston, J.P., Buddenberg, T.E., Mattern, C. Dopaminergic and serotonergic activity in neostriatum and nucleus accumbens enhanced by intranasal administration of testosterone. European Neuropsychopharmacology, 2009, 19(1):53-63. [abstract] [full text]

Pum, M.E., Huston, J.P., Müller, C.P., de Souza Silva, M.A. Light.-induced activity in the activity box is not aversively motivated and does not show between inter-trial habituation. Physiology & Behavior, 2009, 96(3):434-439.  [abstract] [full text]

 

 

2008

de Souza Silva, M.A., Jocham, G., Barros, M., Tomaz, C., Müller, C.P.  Neurokinin3 receptor modulation of the behavioral and neurochemical effects of cocaine in rats and monkeys. Reviews in the Neurosciences. 2008, 19:101-111.[abstract]

Topic, B., Oitzl, M.S., Meijer, O.C., Huston, J.P., de Souza Silva, M.A. Differential susceptibility to extinction-induced despair and age-dependent alterations in hypothalamic-pituitary-adrenal axis and neurochemical markers. Neuropsychobiology, 2008, 58(3-4):138-153. [abstract] [full text]


Dere, E., Zlomuzica, A., Viggiano D., Ruocco, L.A., Watanabe, T., Sadile, A.G., Huston, J.P., de Souza Silva, M.A. Episodic-like and procedural memory impairments in histamine H1-R knockout mice coincide with changes in acetylcholine esterase activity in the hippocampus and cerebellum. Neuroscience, 2008, 157:196-203. [abstract] [full text]


de Souza Silva, M.A., Topic, B., Huston,J.P. , Mattern, C. Intranasal administration of progesterone increases dopaminergic activity in amygdala and neostriatum of male rats. Neuroscience, 2008, 157:196-203. [abstract] [full text]

Carvalho, M.C., Masson, S., Brandao, M.L., de Souza Silva, M.A. Anxiolytic-like effects of substance P administration into the dorsal, but not ventral, hippocampus and its influence on serotonin. Peptides, 2008, 29(7):1191-1200. [abstract] [full text] .


Pum, M.E., Carey, R.J., Huston, J.P., Müller, C.P. Role of the medial prefrontal, entorhinal, and occipital 5-HT in cocaine induced place preference and hyperlocomotion: evidence for multiple dissociations. Psychopharmacology (Berl), 2008, 201(3):391-403. [abstract] [full text]

Topic, B., Huston, J.P., Namestkova, K., Zhum S.-W., Mohammed, A.H., Schulz, D.  Extinction-induced "despair" in aged and adult rats: Links to neurotrophins in frontal cortex and hippocampus. Neurobiology of  Learning and Memory, 2008, 90:519-526. [abstract] [full text]


Carey, R.J., Huston, J.P., Müller C.P. Pharmacological inhibition of dopamine and serotonin activity blocks spontaneous and cocaine-activated behaviour. Progress in Brain Research, 2008,172:347-360. [abstract] [full text]

Barros, M., Maior, R.S., Huston, J.P., Tomaz, C.  Predatory stress as an experimental strategy to measure fear and anxiety-related behaviors in non-human primates. Reviews in the Neurosciences, 2008, 19(2-3):157-169. [abstract]

Carey, R.J., Shanahan, A., Damianopoulos, E.N., Müller, C.P., Huston, J.P. Behavior selectively elicited by novel stimuli: modulation by the 5-HT1A agonist 8-OHDPAT and antagonist WAY-100635. Behavioural Pharmacology, 2008, 19(4):361-364. [abstract]

Ponomarenko, A.A., Li, J.S., Korotkova, T.M., Huston, J.P., Haas, H.L. Frequency of network synchronization in the hippocampus marks learning. European Journal of  Neurosciience, 2008, 27(11):3035-3042. [abstract] [full text]

Zlomuzica, A., Dere, E., Huston,  J.P., de Souza Silva, M.A. NK(3) receptor agonism promotes episodic-like memory in mice. Neurobiology of Learning and Memory,. 2008, 90(2):420-425. [abstract] [full text]

Buddenberg, T.E., Topic, B., Mahlberg, E.D., de Souza Silva, M.A., Huston, J.P., Mattern, C. Behavioral Actions of Intranasal Application of Dopamine: Effects on Forced Swimming, Elevated Plus-Maze and Open Field Parameters. Neuropsychobiology, 2008, 57(1-2):70-79. [abstract] [full text]

Dere, E., Zheng-Fischhöfer, Q., Viggiano, D., Gironi Carnevale, U.A., Ruocco, L.A., Zlomuzica, A., Schnichels, M., Willecke, K., Huston, J.P., Sadile, A.G. Connexin31.1 deficiency in the mouse impairs object memory and modulates open-field exploration, acetylcholine esterase levels in the striatum, and cAMP response element-binding protein levels in the striatum and piriform cortex. Neuroscience, 2008, 153(2):396-405. [abstract] [full text

Pum, M.E., Huston, J.P., De Souza Silva, M.A., Müller, C.P. Visual sensory-motor gating by serotonin activation in the medial prefrontal and occipital, but not in the rhinal, cortices in rats. Neuroscience, 2008, 153(2):361-72. [abstract] [full text

Zlomuzica, A., Viggiano, D., De Souza Silva, M.A., Ishizuka, T., Gironi Carnevale, U.A., Ruocco, L.A., Watanabe, T., Sadile, A.G., Huston J.P., Dere, E. The histamine H1-receptor mediates the motivational effects of novelty. European Journal of Neuroscience, 2008, 27(6):1461-74. [abstract] [full text]

Müller, C.P., Carey, R.J., Wilkisz, M., Schwenzner, S., Jocham, G., Huston, J.P., De Souza Silva, M.A. Acute anxiolytic effects of cocaine: the role of test latency and activity phase. Pharmacology, Biochemistry, and Behavior, 2008, 89(2):218-26. [abstract] [full text]

Carey, R.J., DePalma, G., Shanahan, A., Damianopoulos, E.N., Müller, C.P., Huston, J.P. Effects on spontaneous and cocaine-induced behavior of pharmacological inhibition of noradrenergic and serotonergic systems. Pharmacology, Biochemistry, and Behavior, 2008, 89(1):54-63. [abstract] [full text]

de Souza Silva, M.A., Topic, B., Huston, J.P., Mattern, C. Intranasal dopamine application increases dopaminergic activity in the neostriatum and nucleus accumbens and enhances motor activity in the open field. Synapse, 2008, 62(3):176-84. [abstract] [full text]

2007

de Souza Silva, M.A., Topic, B., Lamounier-Zepter, V., Huston, J.P., Tomaz, C., Barros M. Evidence for hemispheric lateralization in the marmoset (Callithris penicillata) based on lateralization of behavioral/neurochemicaal correlations. Brain Research Bulletin, 2007, 74(6):416-28. [abstract] [full text]
 
Schulz, D., Kouri, C., Huston, J.P. Behavior on the water maze platform: relationship to learning and open field exploration in aged and adult rats. Brain Research Bulletin, 2007, 74(4): 206-215. [abstract] [full text]

Zlomuzica, A., de Souza Silva, M.A., Huston, J.P.,  Dere, E. NMDA-Receptor modulation by D-cycloserine promotes episodic-like memory in mice. Psychopharmacology (Berl). 2007, 193(4):503-509. [abstract] [full text]

Pum, M., Carey, R.J., Huston, J.P., Muller, C.P.  Dissociating effects of cocaine and d-amphetamine on dopamine and serotonin in the perirhinal, entorhinal, and prefrontal cortex of freely moving rats. Psychopharmacology (Berl). 2007, 193(3):375-390. [abstract] [full text]

Jocham, G., Lauber, A.C., Muller, C.P., Huston, J.P., de Souza Silva, M.A.  Neurokinin(3) receptor activation potentiates the psychomotor and nucleus accumbens dopamine response to cocaine, but not its place conditioning effects. European  Journal of  Neuroscience. 2007 Apr;25(8):2457-72. [abstract] [full text]

Topic, B., Tavares, M.C., Tomaz, C., Mattern, C.  Prolonged effects of intra-nasally administered testosterone on proceptive behavior in female capuchin monkeys (Cebus apella). Behavioural Brain Research, 2007, Vol. 179(1): 60-68. [abstract] [full text]

Tavares, M.C., Topic, B., Abreu, C., Waga, I., Gomes, U., Tomaz, C., Mattern, C. Effects of intra-nasally administered testosterone on sexual proceptive behavior in female capuchin monkeys (Cebus apella). Behavioural Brain Research, 2007, Vol. 179(1): 33-42. [abstract] [full text]

Müller, C.P., Carey, R.J., Huston, J.P., de Souza Silva, M.A. Serotonin and psychostimulant addiction: focus on 5-HT1A-receptors. Progress in Neurobiology, 2007, Vol. 81(3):133-178. [abstract] [full text]

Müller, C.P., Huston, J.P. Dopamine activity in the occipital and temporal cortex of rats: dissociating effects of sensory but not pharmacological stimulation. Synapse, 2007, Vol. 61(4):254-258. [abstract] [full text]

Zheng-Fischhöfer, Q., Schnichels, M., Dere, E., Strotmann, J., McCulloch, F., Kretz, M., Reucher, H., Peti-Peterdi, J., Huston, J.P., Breer, H., Willecke, K. Characterization of connexin30.3-deficient mice suggests a possible
role of connexin30.3 in olfaction. European Journal of cell Biology, 2007, 86(11-12):683-700. [abstract] [full text]

Dere, E., de Souza Silva, M.A., Huston, J.P. The pharmacology, neuroanatomy, and neurogenetics of one-trial object recognition in rodents. Neuroscience & Biobehavioral Reviews, 2007, 31(5): 673-704. [abstract] [full text]

Müller, C.P., de Souza Silva, M.A., Huston, J.P. Double dissociating effects of sensory stimulation and cocaine on serotonin activity in the occipital and temporal cortices. Neuropharmacology, 2007, Vol. 52(3):854-862. [abstract] [full text]

Schulz, D., Buddenberg, T., Huston, J.P. Extinction-induced "despair" in the water maze, exploratory behavior and fear: effects of chronic antidepressant treatment. Neurobiology of Learning and Memory, 2007, 87(4):624-34. [abstract] [full text]

Topic, B., Willuhn, I., Palomero-Gallagher, N., Zilles, K., Huston, J.P., Hasenöhrl, R.U. Impaired maze performance in aged rats is accompanied by increased density of NMDA, 5-HT1a, and  -adrenoceptor binding in hippocampus. Hippocampus, 2007, 17(1):68-77. [abstract] [full text]

Schulz, D., Huston, J.P., Buddenberg, T., Topic, B. "Despair" induced by extinction trials in the water maze: relationship with measures of anxiety in aged and adult rats. Neurobiology of Learning and Memory, 2007, Vol. 87(3):309-323. [abstract] [full text]

De Souza Silva, M.A., Eisel, U.L.M., Huston, J.P., Dere, E. NR2c by NR2B subunit exchange in juvenile mice affects emotionality and 5-HT in the frontal cortex. Genes, Brain and Behavior, 2007, 6(5):465-72. [abstract] [full text]

Kart-Teke, E., Dere, E., Huston, J.P., De Souza Silva, M.A. Reinstatement of episodic-like memory in rats by NK-1 receptor antagonism. Neurobiology of Learning & Memory, 2007, Vol. 87(3):324-331. [abstract] [full text]

2006

Dere, E., Kart-Teke, E., Huston, J.P., De Souza Silva, M.A. The case for episodic memory in animals. Neuroscience & Biobehavioral Reviews, 2006, 30(8):1206-24. [abstract] [full text]

Müller, C.P. and Carey, R.J. (2006) Intracellular 5-HT2C-receptor dephosphorylation: a new target for drug addiction pharmacotherapy. Trends in Pharmacological Sciences, 27(9): 455-458. [abstract] [full text]

Müller, C.P., Topic, B., Huston, J.P., Strohbeck-Kühner, P., Lutz, B., Skopp, G., Aderjan, R., Cannabis und Verkehrssicherheit: Mangelnde Fahreignung nach Cannabiskonsum: Leistungsdefizite, psychologische Indikatoren und analytischer Nachweis. NW Wirtschaftsverlag, Bremerhaven, 2006. [NW-Verlag homepage]

Jocham, G., Lezoch, K., Müller, C.P., Kart-Teke, E., Huston, J.P., De Souza Silva, M.A.  Neurokinin3 receptor antagonism attenuates cocaine's behavioural activating effects yet potentiates its dopamine-enhancing action in the nucleus accumbens core. European Journal of Neuroscience, 2006, 24(6):1721-1732. [abstract] [full text]

De Souza Silva, M.A., Mello, E.L., Müller, C.P., Jocham, G., Maior, R.S., Huston, J.P., Tomaz, C., Barros, M. Interaction of the tachykinin NK3 receptor agonist senktide with behavioral effects of cocaine in marmosets (Callithrix penicillata). Peptides, 2006, 27:2214-2223. [abstract] [full text]

De Souza Silva, M.A., Mello, E.L., Müller, C.P., Jocham, G., Maior, R.S., Huston, J.P., Tomaz, C., Barros, M., The tachykinin NK3 receptor antagonist SR142801 blocks the behavioral effects of cocaine in marmoset monkeys. European Journal of  Pharmacology, 2006, 536(3): 269-278. [abstract] [full text]

De Souza Silva, M.A., Dolga, A., Pieri, I., Marchetti, L., Eisel, U.L.M., Huston, J.P. Cholinergic cells in the nucleus basalis of mice express the NMDA-receptor subunit NR2C and its replacement by NR2B subunit by the NR2B subunit enhances frontal and amygdaloid ACh levels. Genes, Brain and Behavior, 2006, 5:552-560. [abstract] [full text]

Li, J.S., Krauth, J., Huston, J.P. Operant behavior of rats under fixed-interval reinforcement schedules: A dynamical Analysis vie the extended return map. Nonlinear Dynamics for Psychology and Life Science, 2006, 10(2):215-240. [abstract]

Müller, C.P., Huston, J.P. Determining the region-specific contributions of 5-HT receptors to the psychostimulant effects of cocaine. Trends Pharmacological Sciences, 2006, 27(2): 105-112. [abstract] [full text]

Kart-Teke, E., De Souza Silva, M.A., Huston, J.P., Dere, E. Wistar rats show episodic-like memory for unique experiences. Neurobiology of Learning and Memory, 2006, 85(2): 173-182. [abstract] [full text]

2005

Bert, B., Dere, E., Kusserow, H., Theuring, F., Huston, J.P., Fink, H. Transient overexpression of the 5-HT1A receptor impairs water-maze but not hole-board performance. Neurobiology of Learning and Memory, 2005, 84:57-68. [abstract] [full text]

Carey, R.J., DePalma, G., Damianopoulos, E., Shanahan, A., Müller, C.P., Huston, J.P. Pharmacological inhibition of DA - and 5-HT-activity blocks spontaneous and cocaine activated behavior: Reversal by chronic cocaine treatment. Brain Research, 2005, 1047:194-204. [abstract] [full text]

Carey, R.J., DePalma, G., Damianopoulos, E., Shanahan, A., Müller, C.P., Huston, J.P. Evidence that the 5-HT1A autoreceptor is an important pharmacological target for the modulation of cocaine behavioural stimulant effects. Brain Research, 2005, 1034:162-171. [abstract] [full text]

Dere, E., Huston, J.P., De Souza Silva, M.A. Intergrated Memory for objects, places and temporal order: evidence for episodic-like memory in mice. Neurobiology of Learning and Memory, 2005, 84 (3):214-221. [abstract] [full text]

Dere, E., Huston, J. P., De Souza Silva, M. A. Episodic-like memory in mice: Simultaneous assessment of object, place and temporal order memory. Brain Research Protocols 2005, 16(1-3): 10-19. [abstract] [full text]

Frisch, C., De Souza-Silva, M.A., Söhl, G., Güldenagel, M., Willecke, K., Huston, J.P., Dere, E. Stimulus complexity dependent memory impairment and changes in motor performance after deletion of the neuronal gap junction protein connexin36 in mice. Behavioural Brain Research, 2005, 157:177-185. [abstract] [full text

Luhmann, H.J., Huston, J.P., Hasenöhrl, R.U. Contralateral increase in thigmotactic scanning following unilateral barrel-cortex lesion in mice. Behavioural Brain Research, 2005, 157:39-43. [abstract] [full text

Macedo, C.E., Martinez, R.C.R., De Souza Silva, M.A., Brandao, M.L. Increases in extracellular levels of 5-HT and dopamine in the basolateral, but not central, nucleus of amygdala induced by aversive stimulation of the inferior colliculus. European Journal of Neuroscience, 2005, 21:1131-1138. [abstract] [full text]

Meijer, O.C., Topic, B., Steenbergen, P.J., Jocham, G., Huston, J.P., Oitzl, O.S. Correlations between hypothalamus-pituitary-adrenal axis parameters depend on age and learning capacity. Endocrinology, 2005, 146:1372-1381. [abstract] [full text]

Mello Jr., E.L., Maior, R.S., Carey, R.J., Huston, J.P., Tomaz, C., Müller, C.P. Serotonin1A-receptor antagonism blocks psychostimulant properties of diethylpropion in marmosets (Callithrix penicillata). European Journal of Pharmacology, 2005, 511:43-52. [abstract] [full text

Sergeeva, O.A., Schulz, D., Doreulee, N., Ponomarenko, A.A., Selbach, O., Borsch, E., Kircheis, G., Häussinger, D., Huston, J.P., & Haas, H.L. . Deficits in cortico-striatal synaptic plasticity and behavioural habituation in rats with portacaval anastomosis. Neuroscience, 2005, 134(4):1091-1098. [abstract] [full text]

Topic, B., Dere, E., Schulz, D., de Souza Silva, M.A., Jocham, G., Kart, E., Huston, J.P. Aged and adult rats compared in acquisition and extinction of escape from the water maze: focus on individual differences. Behavioral Neuroscience, 2005, 119:127-144. [abstract] [full text]

 

2004

Barros, M., De Souza Silva, M.A., Huston, J.P., Tomaz, C. Multi-behavioral analysis of fear and anxiety before, during, and after experimentally induced predatory stress in Callithrix penicillata. Pharmacology, Biochemistry & Behavior, 2004, 78:357-367. [full text]

Carey, R.J., De Palma, G., Damianopoulos, E., Hopkins, A., Shanahan, A., Müller, C.P., Huston, J.P. Dopaminergic and serotonergic autoreceptor stimulation effects are equivalent and additive in the suppression of spontaneous and cocaine induced locomotor activity. Brain Research, 2004, 1019(1-2):134-143. [full text]

Carey, R.J., De Palma, G., Damianopoulos, E., Müller, C.P., Huston, J.P. The 5-HT1A receptor and behavioral activation : effects of 8-OH-DPAT upon spontaneous and cocaine induced behavior. Psychopharmacology, 2004, 177:46-54. [abstract] [full text]

Dere, E., De Souza Silva, M.A., Huston, J.P. Higher order memories for objects encountered in different spatio-temporal contexts in mice: evidence for episodic memory. Reviews in the Neurosciences, 2004, 15:231-240. [abstract]

Dere, E., De Souza-Silva, M.A., Spieler, R.E., Lin, J.S., Ohtsu, H., Haas, H.L., Huston, J.P. Changes in motoric, exploratory and emotional behaviors and neuronal ACh content and 5-HT turnover in histidine-decarboxylase KO-mice. European Journal of Neuroscience, 2004, 20:1051-1058. [abstract] [full text]

Hasenöhrl, R.U. , Huston, J.P. Histamine. In: Memories are Made of These: From Messengers to Molecules (ED. G. Riedel & B. Platt), Landes Bioscience, (2004), chapter 2.8.

Kart, E., Jocham, G., Müller, C.P., Schlömer, C., Brandão, M.L., Huston, J.P., de Souza Silva, M.A. Neurokinin-1 receptor antagonism by SR140333: enhanced in vivo ACh in the hippocampus and promnestic post-trial effects. Peptides, 2004, 25(11):1959-1969. [abstract] [full text]

Müller, C.P., Knoche, A., Huston, J.P. Benzoylecgonine as an indicator of neuropsychological deficits after acute and chronic cocaine abuse: an overview. In: XIII. GTFCh-Symposium: Ausgewählte Aspekte der Forensischen Toxikologie, (Ed. F. Pragst & R. Aderjan), Verlag Dr. Dieter Helm, Heppenheim, 2004, pp. 440-445.

Müller, C.P., Knoche, A., Huston, J.P. Die Neuropsychologischen Effekte von Kokain. Zeitschrift für Neuropsychologie, 2004, 15:41-59.

Müller, C.P., Thönnessen, H., Barros, M., Tomaz, C., Carey, R.J., Huston, J.P. Hippocampus 5-HT1A-receptors attenuate cocaine-induced hyperlocomotion and the increase in hippocampal but not nucleus accumbens 5-HT. Hippocampus, 2004, 14:710-721. [abstract] [full text]

Müller, C.P., Thönnessen, H., De Souza Silva, M.A., Fink, H., Bert, B., Carey, R.J., Huston, J.P. Nucleus accumbens serotonin 1A-receptors control cocaine-induced hyperactivity but not local serotonin increase: an in-vivo microdialysis study. Neuropharmacology, 2004, 47:205-215. [abstract] [full text]

Müller, C.P., Thönnessen, H., Jocham, G., Barros, M., Tomaz, C., Carey, R.J. and Huston, J.P., Cocaine-induced "active immobility" and its modulation by the serotonin1A-receptor. Behavioural Pharmacology, 2004, 15(7):481-493. [abstract] [full text]

Schlett, K., Pieri, I., Metzger, F., Marchetti, L., Steigerwald, F., Dere, E., Kirilly, D., Tárnok, K., Barabás, B., Varga, A., Gerspach, J., Huston, J.P., Pfizenmaier, K., Köhr, G., Eisel, U.L.M. Long-term NR2B expression in the cerebellum alters granule cell development and leads to NR2A downregulation and motor deficits. Molecular & Cellular Neuroscience, 2004, 27:215-226. [abstract] [full text]

Schulz, D., Sergeeva, O., Ianovskii, E., Luhmann, H.J., Haas, H.L., Huston, J.P. Behavioral parameters in aged rats are related to LTP and gene expression of ChAT and NMDA-NR2 subunits in the striatum. European Journal of Neuroscience, 2004, 19:1373-1383. [abstract] [full text]

Schulz, D. Topic, B. De Souza Silva, M.A., Huston, J.P. Extinction-induced immobility in the water maze and its neurochemical concomitants in aged and adult rats: A possible model for depression? Neurobiology of Learning and Memory, 2004, 82:128-141. [abstract] [full text]

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Responsible for the content: E-MailProf. Joseph P. Huston